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CRBN ligand-109

CRBN ligand-109 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.

Product Specifications

CAS Number

2758533-77-4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.11

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C(C1=C(F)C=C(Br)C=C1F)CC2)NC2=O

Molecular Formula

C11H8BrF2NO2

Molecular Weight

304.09

Precautions

H302, H315, H319, H335

References & Citations

[1]Miletić N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20 (2) :507-521.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Available Sizes

Frequently Asked Questions

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