Melicopine
Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum, with IC50 values of 29.7 and 33.7 µg/mL, respectively. Melicopine is cytotoxic to prostate cancer cells PC-3M and LNCaP (IC50 values of 47.9 and 37.8 µg/mL), but has no effect on non-cancerous HEK293 cells (IC50 greater than 100 µg/mL) . Melicopine holds promise for research in anticancer and anti-infection fields[1].
Product Specifications
CAS Number
568-01-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Insecticide; Parasite
Related Pathways
Anti-infection; Others
Field of Research
Cancer; Infection
Smiles
O=C1C2=C(N(C)C3=C4OCOC4=C(C(OC)=C13)OC)C=CC=C2
Molecular Formula
C17H15NO5
Molecular Weight
313.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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