LDLR regulator-1
LDLR regulator-1 (Compound 7b) is a regulator of the low-density lipoprotein receptor (LDLR), capable of increasing the mRNA expression of LDLR[1].
Product Specifications
CAS Number
[6656-19-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
LDLR
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Purity
99.89
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C(C=C2CN3CCC4=CC5=C(C=C4C3CC2=C1)OCO5)OC
Molecular Formula
C20H21NO4
Molecular Weight
339.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Li Y H, et al. Berberine Analogues as a novel class of the low-density-lipoprotein receptor up-regulators: synthesis, structure− activity relationships, and cholesterol-lowering efficacy[J]. Journal of Medicinal Chemistry, 2009, 52 (2) : 492-501.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W423578/LDLR-regulator-1-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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