LDLR regulator-1

LDLR regulator-1 (Compound 7b) is a regulator of the low-density lipoprotein receptor (LDLR), capable of increasing the mRNA expression of LDLR[1].

Product Specifications

CAS Number

[6656-19-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

LDLR

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Purity

99.89

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC1=C(C=C2CN3CCC4=CC5=C(C=C4C3CC2=C1)OCO5)OC

Molecular Formula

C20H21NO4

Molecular Weight

339.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Li Y H, et al. Berberine Analogues as a novel class of the low-density-lipoprotein receptor up-regulators: synthesis, structure− activity relationships, and cholesterol-lowering efficacy[J]. Journal of Medicinal Chemistry, 2009, 52 (2) : 492-501.