(Rac) -BX 048

(Rac) -BX 048 is a BX 048 racemate. BX 048 is a P2Y12 receptor antagonist. BX 048 inhibits ADP-induced platelet aggregation in human, dog and rat whole blood. BX 048 also inhibits Arachidonic acid (HY-109590) induced platelet aggregation (IC50 of 15 μM) [1].

Product Specifications

CAS Number

[478005-11-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

P2Y Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C(O)CCC(NC(C1=NC2=CC(C)=CC=C2C(OC(C)(C)C(O)=O)=C1)=O)C(N3CCN(C(OCC)=O)CC3)=O

Molecular Formula

C27H34N4O9

Molecular Weight

558.58

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Post JM, et al. Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II) : pharmacodynamic and pharmacokinetic characterization. Thromb Res. 2008;122 (4) :533-40.