4-Methylamphetamine (hydrochloride)

4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces hypothermia in rats by binding to the 5-HT1A receptor. Additionally, 4-Methylamphetamine hydrochloride acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase the extracellular levels of these neurotransmitters. 4-Methylamphetamine hydrochloride can be used in the study of neurological disorders[1][2].

Product Specifications

CAS Number

[41632-56-8]

Product Name Alternative

4-MA (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

5-HT Receptor; Dopamine Receptor; Monoamine Transporter

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.86

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

NC(CC1=CC=C(C)C=C1)C.Cl

Molecular Formula

C10H16ClN

Molecular Weight

185.69

Precautions

H302, H315, H319, H335

References & Citations

[1]Rubio M, et al. Serotonin is involved in the psychostimulant and hypothermic effect of 4-methylamphetamine in rats. Neurosci Lett. 2015 Mar 17;590:68-73. |[2]Blanckaert P, et al. 4-Methyl-amphetamine: a health threat for recreational amphetamine users. J Psychopharmacol. 2013 Sep;27 (9) :817-22.