Caspase-3-IN-2

Caspase-3-IN-2 (Compound 4d) is the inhibitor for α-Chymotrypsin. Caspase-3-IN-2 also exhibits inhibitory activity against HIV protease and caspase 3 with an inhibition rate of 57% and 51% at 100 μM[1].

Product Specifications

CAS Number

[62252-25-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Caspase; HIV Protease; Ser/Thr Protease

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

COC1=C(C2=C(C=C(C=C2)[N+](=O)[O-])C(=O)O1)Cl

Molecular Formula

C10H6ClNO5

Molecular Weight

255.61

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Bihel F, et al., Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease. Bioorg Med Chem. 2003 Jul 17;11 (14) :3141-52.