CbzNH-PEG4-CH2COOH
CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
Product Specifications
CAS Number
[1451362-51-8]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Smiles
O=C(O)COCCOCCOCCOCCNC(=O)OCC1=CC=CC=C1
Molecular Formula
C18H27NO8
Molecular Weight
385.41
Precautions
P264-P280-P302+P352-P362+P364
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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