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Diosmetin-3-O-glucuronide

Diosmetin-3-O-glucuronide is a major circulating metabolite of Diosmetin in plasma and in urine. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity[1].

Product Specifications

CAS Number

152503-50-9

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Cytochrome P450; Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

O=C1C=C(C2=CC=C(OC)C(O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](C(O)=O)O3)O)O)O)=C2)OC4=C1C(O)=CC(O)=C4

Molecular Formula

C22H20O12

Molecular Weight

476.39

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Silvestro L, et al. Confirmation of diosmetin 3-O-glucuronide as major metabolite of diosmin in humans, using micro-liquid-chromatography-mass spectrometry and ion mobility mass spectrometry. Anal Bioanal Chem. 2013 Oct;405 (25) :8295-310.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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