Diosmetin-3-O-glucuronide
Diosmetin-3-O-glucuronide is a major circulating metabolite of Diosmetin in plasma and in urine. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity[1].
Product Specifications
CAS Number
152503-50-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Cytochrome P450; Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C1C=C(C2=CC=C(OC)C(O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](C(O)=O)O3)O)O)O)=C2)OC4=C1C(O)=CC(O)=C4
Molecular Formula
C22H20O12
Molecular Weight
476.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Silvestro L, et al. Confirmation of diosmetin 3-O-glucuronide as major metabolite of diosmin in humans, using micro-liquid-chromatography-mass spectrometry and ion mobility mass spectrometry. Anal Bioanal Chem. 2013 Oct;405 (25) :8295-310.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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