3-Hydroxyvalproic acid
3-Hydroxyvalproic acid (3-Hydroxy VPA) is a metabolite of valproic acid. 3-Hydroxyvalproic acid is a weak inhibitor of enzymes related to the mitochondrial β-oxidation pathway. 3-Hydroxyvalproic acid is promising for research of diseases related to abnormal valproic acid metabolism[1][2][3].
Product Specifications
CAS Number
58888-84-9
Product Name Alternative
3-Hydroxy VPA
UNSPSC
12352211
Hazard Statement
H302-H312-H332
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
CCC(O)C(CCC)C(O)=O
Molecular Formula
C8H16O3
Molecular Weight
160.21
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Heinemeyer G, et al. Oxidation and glucuronidation of valproic acid in male rats--influence of phenobarbital, 3-methylcholanthrene, beta-naphthoflavone and clofibrate. Biochem Pharmacol. 1985 Jan 1;34 (1) :133-9.|[2]Prickett KS, et al. Metabolism of valproic acid by hepatic microsomal cytochrome P-450. Biochem Biophys Res Commun. 1984 Aug 16;122 (3) :1166-73.|[3]Bello-Ramírez AM, et al. Do structural properties explain the anticonvulsant activity of valproate metabolites? A QSAR analysis. Epilepsia. 2002 May;43 (5) :475-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
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