Actiphenol
Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC50s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide[2].
Product Specifications
CAS Number
526-02-3
UNSPSC
12352005
Hazard Statement
H301
Target
Antibiotic; Drug Intermediate; Influenza Virus
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C1NC(CC(CC(C2=C(O)C(C)=CC(C)=C2)=O)C1)=O
Molecular Formula
C15H17NO4
Molecular Weight
275.30
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]Ji XY, et al. Synthesis and antiviral activities of synthetic glutarimide derivatives. Chem Pharm Bull (Tokyo) . 2010 Nov;58 (11) :1436-41. |[2]Yin M, et al. Cycloheximide and actiphenol production in Streptomyces sp. YIM56141 governed by single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase. Org Lett. 2014 Jun 6;16 (11) :3072-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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