Glutathione monoethyl ester
Glutathione monoethyl ester is a glutathione derivative that can protect motor neuron cells NSC-34 from pathology damage caused by mutations in TDP-43, including reducing aggregation formation, nuclear clearance, reactive oxygen species generation, and cell death[1].
Product Specifications
CAS Number
118421-50-4
UNSPSC
12352211
Hazard Statement
H315-H319-H335
Target
Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
OC(CNC([C@H](CS)NC(CC[C@H](N)C(O)=O)=O)=O)=O.CCO
Molecular Formula
C12H21N3O6S
Molecular Weight
335.38
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Tong Chen, et al. Glutathione monoethyl ester prevents TDP-43 pathology in motor neuronal NSC-34 cells. Neurochem Int. 2018 Jan:112:278-287.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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