Gentisuric acid (Standard)
Gentisuric acid (Standard) is the analytical standard of Gentisuric acid. This product is intended for research and analytical applications. Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM) . Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316) [1][2].
Product Specifications
UNSPSC
12352005
Target
Drug Metabolite; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
OC1=CC(C(NCC(O)=O)=O)=C(O)C=C1
Molecular Formula
C9H9NO5
Molecular Weight
211.17
References & Citations
[1]DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383 (1) :46-55.|[2]Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61 (2-3) :113-9.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W338852R/
Scientific Category
Reference Standards
CAS Number
[25351-24-0]
Available Sizes
Curated Selection
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