Gentisuric acid (Standard)

Gentisuric acid (Standard) is the analytical standard of Gentisuric acid. This product is intended for research and analytical applications. Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM) . Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316) [1][2].

Product Specifications

CAS Number

[25351-24-0]

UNSPSC

12352005

Target

Drug Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

OC1=CC(C(NCC(O)=O)=O)=C(O)C=C1

Molecular Formula

C9H9NO5

Molecular Weight

211.17

References & Citations

[1]DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383 (1) :46-55.|[2]Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61 (2-3) :113-9.