4- (2-Octylamino) diphenylamine

4- (2-Octylamino) diphenylamine is an aromatic amine antioxidant, which is toxic to V. fischeri with an IC50 value of 0.68 mg/mL. 4- (2-Octylamino) diphenylamine induces skin sensitization and contact dermatitis in a local lymph node assay in mice. 4- (2-Octylamino) diphenylamine can be used as an additive in rubber[1][2][3].

Product Specifications

CAS Number

[15233-47-3]

UNSPSC

12352005

Hazard Statement

H302+H312+H332-H315-H319

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Smiles

CC(CCCCCC)NC(C=C1)=CC=C1NC2=CC=CC=C2

Molecular Formula

C20H28N2

Molecular Weight

296.45

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Wang W, et al. Toxicity of substituted p-phenylenediamine antioxidants and their derived novel quinones on aquatic bacterium: Acute effects and mechanistic insights. J Hazard Mater. 2024 May 5;469:133900.|[2]Kawakami T, et al. Characterization of synthetic turf rubber granule infill in Japan: Rubber additives and related compounds. Sci Total Environ. 2022 Sep 20;840:156716.|[3]Yamano T, et al. Skin sensitization potency and cross-reactivity of p-phenylenediamine and its derivatives evaluated by non-radioactive murine local lymph node assay and guinea-pig maximization test. Contact Dermatitis. 2009 Apr;60 (4) :193-8.