4-Chlorochalcone
4-Chlorochalcone (Compound 3) is a monoamine oxidase inhibitor (hMAO-B: IC50 = 0.082 μM, hMAO-A: IC50 = 9.95 μM) . 4-Chlorochalcone also exhibits inhibitory activity against cholinesterase (AChE: IC50 = 2.79 μM) . 4-Chlorochalcone is a chalcone derivative[1].
Product Specifications
CAS Number
956-04-7
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Cholinesterase (ChE) ; Monoamine Oxidase
Related Pathways
Neuronal Signaling
Field of Research
Others
Purity
99.32
Smiles
O=C(C=CC1=CC=C(Cl)C=C1)C=2C=CC=CC2
Molecular Formula
C15H11ClO
Molecular Weight
242.70
Precautions
H315, H319, H335
References & Citations
[1]Oh JM, et al. Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives. Int J Biol Macromol. 2019 Sep 15;137:426-432.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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