4-Chlorochalcone

4-Chlorochalcone (Compound 3) is a monoamine oxidase inhibitor (hMAO-B: IC50 = 0.082 μM, hMAO-A: IC50 = 9.95 μM) . 4-Chlorochalcone also exhibits inhibitory activity against cholinesterase (AChE: IC50 = 2.79 μM) . 4-Chlorochalcone is a chalcone derivative[1].

Product Specifications

CAS Number

[956-04-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Cholinesterase (ChE) ; Monoamine Oxidase

Related Pathways

Neuronal Signaling

Field of Research

Others

Purity

99.32

Smiles

O=C(C=CC1=CC=C(Cl)C=C1)C=2C=CC=CC2

Molecular Formula

C15H11ClO

Molecular Weight

242.70

Precautions

H315, H319, H335

References & Citations

[1]Oh JM, et al. Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives. Int J Biol Macromol. 2019 Sep 15;137:426-432.