2,4-Dinitrobenzenesulfonic acid (sodium salt)

2,4-Dinitrobenzenesulfonic acid (sodium salt) is a hapten. 2,4-Dinitrobenzenesulfonic acid (sodium salt) can induce the proliferation of primary lymphocytes and epithelial cells isolated from guinea pigs that are sensitized to 2, 4-DNCB. 2,4-Dinitrobenzenesulfonic acid (sodium salt) inhibits contact sensitivity induced by 2, 4-DNCB in guinea pigs. 2,4-Dinitrobenzenesulfonic acid (sodium salt) can induce ulcerative colitis in rodent models[1][2][3].

Product Specifications

CAS Number

[885-62-1]

Product Name Alternative

Sodium 2,4-dinitrobenzenesulfonate; DNBS (sodium salt) ; DNBSO (sodium salt)

UNSPSC

12352005

Hazard Statement

H228, H315, H319, H335

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Inflammation/Immunology

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=[N+]([O-])C1=CC([N+]([O-])=O)=C(S(=O)(O[Na])=O)C=C1

Molecular Formula

C6H3N2NaO7S

Molecular Weight

270.15

Precautions

H228, H315, H319, H335

References & Citations

[1]Li, Q., & Aoyama, K. (1991) . In vitro evaluation on contact sensitivity from DNCB and DNBS using lymphocyte blastogenesis response test. Sangyo igaku. Japanese journal of industrial health, 33 (6), 509–518. |[2]Frey, J. R., et al., (1971) . Studies on the induction of immunological tolerance by antigen in guinea-pigs already sensitized to dinitrochlorobenzene. Clinical and experimental immunology, 8 (1), 131–139. |[3]Kim, S., et al., (2020) . A Colon-Targeted Prodrug, 4-Phenylbutyric Acid-Glutamic Acid Conjugate, Ameliorates 2,4-Dinitrobenzenesulfonic Acid-Induced Colitis in Rats. Pharmaceutics, 12 (9), 843.