HCAI/II/XII-IN-1
HCAI/II/XII-IN-1 (compound 7) is a human carbonic anhydrase hCAI/II/XII inhibitor, with Ki values of 78.5, 9.1, 605, 7.7 and 3.7 nM[1].
Product Specifications
CAS Number
[100142-87-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=S(C1=CC=C(C2=CC=C(N)C=C2)C=C1)(N)=O
Molecular Formula
C12H12N2O2S
Molecular Weight
248.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Giuseppe La Regina, et al. Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. J Med Chem. 2015 Nov 12;58 (21) :8564-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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