Trihexyl phosphate
Trihexyl phosphate is an organophosphate flame retardant. Trihexyl phosphate causes mitochondrial impairment and induces cell apoptosis in CHO cells. Trihexyl phosphate promotes the proliferation of human breast cancer cells (MCF-7) in a dose-dependent manner and exerts estrogenicity via ERα-independent pathways[1].
Product Specifications
CAS Number
2528-39-4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Related Pathways
Apoptosis
Field of Research
Cancer
Purity
99.00
Smiles
CCCCCCOP(=O)(OCCCCCC)OCCCCCC
Molecular Formula
C18H39O4P
Molecular Weight
350.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Li Z, et al. Cytotoxic Screening and Transcriptomics Reveal Insights into the Molecular Mechanisms of Trihexyl Phosphate-Triggered Hepatotoxicity. Environ Sci Technol. 2020 Sep 15;54 (18) :11464-11475. |[2]Ji X, et al. In vitro estrogen-disrupting effects of organophosphate flame retardants. Sci Total Environ. 2020 Jul 20;727:138484.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
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