Benzylaspartic acid
Benzylaspartic acid (IEM-1770), a derivative of aspartic acid, is a NMDA agonist. Benzylaspartic acid has antidepressant activity. Benzylaspartic acid blocks alcohol-abstinence syndrome (AAS) development in chronic alcohol drinking rat models. Benzylaspartic acid can be used for depression research[1][2].
Product Specifications
CAS Number
[5555-22-6]
Product Name Alternative
IEM-1770
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Drug Derivative; iGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
C1=CC=C(C=C1)CNC(CC(=O)O)C(=O)O
Molecular Formula
C11H13NO4
Molecular Weight
223.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Schlösser R, et al. Altered benzodiazepine receptor sensitivity in alcoholism: A study with fMRI and acute lorazepam challenge[J]. European Neuropsychopharmacology, 2002, 12: 397-398.|[2]Petrov VI, et al. Antidepressant activity of aspartic acid derivatives. Bull Exp Biol Med. 2001 Apr;131 (4) :342-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Curated Selection
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