1,3,5-Triphenyl-2-pyrazoline

1,3,5-Triphenyl-2-pyrazoline (Compound 12) is a pyrazoline derivative. 1,3,5-Triphenyl-2-pyrazoline exhibits weak cytotoxicity against K562 and Jurkat cells, with an IC50 of greater than 300 μM and 297.7 μM, respectively. 1,3,5-Triphenyl-2-pyrazoline has a predicted human intestinal absorption rate of 100%[1].

Product Specifications

CAS Number

[742-01-8]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer

Smiles

C1(C2=CC=CC=C2)=NN(C3=CC=CC=C3)C(C4=CC=CC=C4)C1

Molecular Formula

C21H18N2

Molecular Weight

298.38

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Santos Bubniak LD, et al. Effects of 1,3,5-triphenyl-4,5-dihydro-1H-pyrazole derivatives on cell-cycle and apoptosis in human acute leukemia cell lines. Can J Physiol Pharmacol. 2017 May;95 (5) :548-563.