4-Acetylaminoantipyrine-d3
4-Acetylaminoantipyrine-d3 is the deuterium labeled 4-Acetylaminoantipyrine. 4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX). 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD[2]. 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation[3].
Product Specifications
CAS Number
342821-66-3
UNSPSC
12352005
Target
COX; Isotope-Labeled Compounds; PGE synthase; SOD
Related Pathways
Immunology/Inflammation; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1N(C2=CC=CC=C2)N(C(C)=C1NC(C([2H])([2H])[2H])=O)C
Molecular Formula
C13H12D3N3O2
Molecular Weight
248.30
References & Citations
[1]Berno CR, et al. Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24. |[2]Teng Y, et al. Insights into potentially toxic effects of 4-aminoantipyrine on the antioxidant enzyme copper-zinc superoxide dismutase. J Hazard Mater. 2013 Nov 15;262:318-24.|[3]Teng Y, et al. The interaction between 4-aminoantipyrine and bovine serum albumin: multiple spectroscopic and molecular docking investigations. J Hazard Mater. 2011 Jun.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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