FGFR1 inhibitor-15
FGFR1 inhibitor-15 (Compound 23) is an FGFR1 inhibitor with an IC50 of 27 μM. FGFR1 inhibitor-15 can be used in the study of cancer[1].
Product Specifications
CAS Number
[459137-97-4]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
FGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C1C(C2=NC3=C(N2)C=CC=C3)=C(N(C1)C4=CC=C(C=C4)F)N
Molecular Formula
C17H13FN4O
Molecular Weight
308.31
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Gryshchenko AA, et al. Design, synthesis and biological evaluation of 5-amino-4- (1H-benzoimidazol-2-yl) -phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1. Bioorg Med Chem. 2016 May 1;24 (9) :2053-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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