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E3 ligase Ligand 56

E3 ligase Ligand 56 is the ligand for E3 ligase Cereblon and can be used for syntheisis of PROTAC CDK9 degrader-11.

Product Specifications

CAS Number

1472731-41-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Purity

99.88

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C(NC1=CC=CC(N)=C1)CC2)NC2=O

Molecular Formula

C11H13N3O2

Molecular Weight

219.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang Y, et al., Identification of a Potent and Selective CDK9 Degrader as a Targeted Therapeutic Option for the Treatment of Small-Cell Lung Cancer. J Med Chem. 2025 Feb 13;68 (3) :2528-2550.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Available Sizes

Frequently Asked Questions

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