E3 ligase Ligand 56
E3 ligase Ligand 56 is the ligand for E3 ligase Cereblon and can be used for syntheisis of PROTAC CDK9 degrader-11 (HY-170978) [1].
Product Specifications
CAS Number
[1472731-41-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Purity
99.88
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C(NC1=CC=CC(N)=C1)CC2)NC2=O
Molecular Formula
C11H13N3O2
Molecular Weight
219.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang Y, et al., Identification of a Potent and Selective CDK9 Degrader as a Targeted Therapeutic Option for the Treatment of Small-Cell Lung Cancer. J Med Chem. 2025 Feb 13;68 (3) :2528-2550.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6241604-01 0.1 mL
CD44V6 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1) (AP)
Ask
View Details MBS6241604-02 5x 0.1 mL
CD44V6 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1) (AP)
Ask
View Details 
247692-AP 100 µL
IRAK3 (Interleukin-1 Receptor-Associated Kinase 3, ASRT5, FLJ13601, IRAK-M, IRAKM) (AP) discontinued
Ask
View Details