E3 ligase Ligand 51
E3 ligase Ligand 51 is the ligand for E3 ligase CRBN that can be used for synthesis of PROTAC BTK Degrader-12 (HY-170413) [1].
Product Specifications
CAS Number
[2703915-71-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.0
Smiles
O=CC1CCN(C2=CC=C(N(C(N3)=O)CCC3=O)C=C2)CC1
Molecular Formula
C16H19N3O3
Molecular Weight
301.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang H, et al., Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inhibitors with e3 ligase ligand and methods of use. WO2021219070
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
