Thalidomide-pinacolborane
Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
Product Specifications
CAS Number
[2229725-98-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Purity
97.0
Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(B4OC(C)(C)C(C)(C)O4)=C3)=O
Molecular Formula
C19H21BN2O6
Molecular Weight
384.19
Precautions
H302, H315, H319, H335
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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