Thalidomide-pinacolborane
Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
Product Specifications
CAS Number
[2229725-98-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Purity
97.0
Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(B4OC(C)(C)C(C)(C)O4)=C3)=O
Molecular Formula
C19H21BN2O6
Molecular Weight
384.19
Precautions
H302, H315, H319, H335
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GWB-534E18 0.05 mg
BTB And CNC Homology 1 Basic Leucine Zipper Transcription Factor 1 (BACH1) Rabbit anti-Human Polyclonal (aa92-104) Antibody
Ask
View Details 
MBS6497815-01 0.1 mL
RICTOR, ID (Rapamycin-insensitive Companion of mTOR, AVO3 Homolog, hAVO3, KIAA1999) (MaxLight 650)
Ask
View Details 
MBS6497815-02 5x 0.1 mL
RICTOR, ID (Rapamycin-insensitive Companion of mTOR, AVO3 Homolog, hAVO3, KIAA1999) (MaxLight 650)
Ask
View Details 
bs-7709R-BF680 100 µL
Retinoic acid induced 17 Antibody, AbBy Fluor™ 680 Conjugated
Ask
View Details