PSF-IN-1
PSF-IN-1 (Compound No.10-3) is a RNA-binding protein (PSF) inhibitor and can effectively inhibit the PSF-RNA interaction (IC50: 2.2 pM) . PSF-IN-1 can increase histone acetylation, inhibit tumor cell proliferation and induce apoptosis. PSF-IN-1 has antitumor activity[1].
Product Specifications
CAS Number
370582-94-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
COC1=CC=C(C=C1)C2=CC(=O)OC3=C2C=CC(=C3O)O
Molecular Formula
C16H12O5
Molecular Weight
284.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Takayama KI, et al. Targeting Epigenetic and Posttranscriptional Gene Regulation by PSF Impairs Hormone Therapy-Refractory Cancer Growth. Cancer Res. 2021 Jul 1;81 (13) :3495-3508.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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