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Trans-4-Aminocyclohexylacetic acid

Trans-4-Aminocyclohexylacetic acid is a PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC FAK degrader 4 (HY-178467) [1].

Product Specifications

CAS Number

[2952-00-3]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

C1C[C@@H](CC[C@H]1CC(=O)O)N

Molecular Formula

C8H15NO2

Molecular Weight

157.21

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Liu C, et al. Structure-guided design of a potent focal adhesion kinase (FAK) degrader via ternary complex modeling and molecular dynamics simulation. Bioorg Chem. 2025 Oct;165:109017.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Curated Selection

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