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7-Hydroxy-4-phenylcoumarin

7-Hydroxy-4-phenylcoumarin is a dual ALDH-2 and MAO inhibitor, with IC50 values of 1.5 and 0.5 µM, respectively[1].

Product Specifications

CAS Number

[2555-30-8]

Product Name Alternative

4-Phenylumbelliferone

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Aldehyde Dehydrogenase (ALDH) ; Monoamine Oxidase

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Metabolic Disease

Purity

96.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C1=CC=C(C=C1)C2=CC(=O)OC3=C2C=CC(=C3)O

Molecular Formula

C15H10O3

Molecular Weight

238.24

Precautions

H315, H319, H335

References & Citations

[1]G Y Gao, et al. Synthesis of potential antidipsotropic isoflavones: inhibitors of the mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway. J Med Chem. 2001 Sep 27;44 (20) :3320-8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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