Tetrahydropapaveroline (hydrobromide)
Tetrahydropapaveroline (Norlaudanosoline) hydrobromide, an isoquinoline alkaloid, is a condensation product of dopamine and dopaldehyde. Tetrahydropapaveroline hydrobromide inhibits [3H]DA uptake with a Ki of 41 μM. Tetrahydropapaveroline hydrobromide can be used for the study of Parkinson's disease and/or alcohol addiction[1][2].
Product Specifications
CAS Number
16659-88-4
Product Name Alternative
Norlaudanosoline (hydrobromide)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
99.82
Smiles
OC1=CC=C(CC2NCCC3=CC(O)=C(C=C32)O)C=C1O.Br
Molecular Formula
C16H18BrNO4
Molecular Weight
368.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhu W, Mantione KJ, Shen L, Lee B, Stefano GB. Norlaudanosoline and nicotine increase endogenous ganglionic morphine levels: nicotine addiction. Cell Mol Neurobiol. 2006;26 (4-6) :1037-1045. |[2]Okada T, et al. Tetrahydropapaveroline and its derivatives inhibit dopamine uptake through dopamine transporter expressed in HEK293 cells. Neurosci Res. 1998 Jan;30 (1) :87-90.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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