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2-CEES

2-CEES is a mustard gas analog forms only DNA monoadducts. 2-CEES induces centrosome amplification in human and mouse cells. 2-CEES induces centrosome amplification and chromosome instability[1].

Product Specifications

CAS Number

[693-07-2]

UNSPSC

12352100

Hazard Statement

H226, H301+H311+H331, H314, H350

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

98.89

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CCSCCCl

Molecular Formula

C4H9ClS

Molecular Weight

124.63

Precautions

H226, H301+H311+H331, H314, H350

References & Citations

[1]Bennett RA, et al. Mustard gas surrogate, 2-chloroethyl ethylsulfide (2-CEES), induces centrosome amplification and aneuploidy in human and mouse cells : 2-CEES induces centrosome amplification and chromosome instability. Cell Biol Toxicol. 2014 Aug;30 (4) :195-205.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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