N-Octanoyl dopamine
N-Octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. N-Octanoyl dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells[1][2].
Product Specifications
CAS Number
105026-81-1
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Smiles
CCCCCCCC(NCCC1=CC=C(O)C(O)=C1)=O
Molecular Formula
C16H25NO3
Molecular Weight
279.37
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Sivakkanan Loganathan, et al. N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. Pharmacol Res. 2019 Dec:150:104503. |[2]Björn B Hofmann, et al. N-Octanoyl-Dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells. Sci Rep. 2019 Dec 18;9 (1) :19338.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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