N-Octanoyl dopamine

N-Octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. N-Octanoyl dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells[1][2].

Product Specifications

CAS Number

[105026-81-1]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Dopamine Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology

Smiles

CCCCCCCC(NCCC1=CC=C(O)C(O)=C1)=O

Molecular Formula

C16H25NO3

Molecular Weight

279.37

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Sivakkanan Loganathan, et al. N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. Pharmacol Res. 2019 Dec:150:104503. |[2]Björn B Hofmann, et al. N-Octanoyl-Dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells. Sci Rep. 2019 Dec 18;9 (1) :19338.