TGN-073
TGN-073 is a facilitator of aquaporin-4 (AQP4), an astroglial water channel. TGN-073 reveals an increase of up to 41% in glymphatic transport in rat brain[1].
Product Specifications
CAS Number
[877459-36-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aquaporin
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.53
Smiles
O=S(C1=CC=CC=C1)(NC2=NC=CC=C2OCC3=CC=CC=C3)=O
Molecular Formula
C18H16N2O3S
Molecular Weight
340.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Alaa Alghanimy, et al. The effect of a novel AQP4 facilitator, TGN-073, on glymphatic transport captured by diffusion MRI and DCE-MRI. PLoS One. 2023 Mar 15;18 (3) :e0282955.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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