ALKBH5-IN-4
ALKBH5-IN-4 (compound 3) is a RNA m6A demethylase ALKBH5 inhibitor with an IC50 of 0.84 μM. ALKBH5-IN-4 shows inhibitory effect on leukemia cells[1].
Product Specifications
CAS Number
[37510-29-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.82
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O)CSC(O)C(C1=CC=CC=C1)=O
Molecular Formula
C10H10O4S
Molecular Weight
226.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Abd El-Haleem AH, et al. Furan- and Furopyrimidine-Based Derivatives: Synthesis, VEGFR-2 Inhibition, and In Vitro Cytotoxicity. ACS Med Chem Lett. 2024 Nov 25;15 (12) :2150-2157.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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