PTCA
PTCA is a potent Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα) ligand with a pKi value of 7.2[1].
Product Specifications
CAS Number
[871326-47-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CaMK
Related Pathways
Neuronal Signaling
Field of Research
Metabolic Disease
Purity
99.72
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CSC(C2=C(Cl)C=CC=C2Cl)=N1)O
Molecular Formula
C10H5Cl2NO2S
Molecular Weight
274.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Tian Y, et al. Structure-Based Virtual Screening Identifies 2-Arylthiazole-4-Carboxylic Acids as a Novel Class of Nanomolar Affinity Ligands for the CaMKIIα Hub Domain. J Med Chem. 2025 Jan 28.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Available Sizes
Curated Selection
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