NP-184

NP-184 is a novel orally active antithrombotic agent. NP-184 selectively inhibits TXA2 synthase activity with an IC50 value of 4.3 μM. NP-184 has antiplatelet and antithrombotic activities. NP-184 can be used in the research of thromboembolic diseases[1].

Product Specifications

CAS Number

[78706-11-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

CC1=CC=C(C2=NC3=CC=CC=C3N2)O1

Molecular Formula

C12H10N2O

Molecular Weight

198.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Kuo HL, et al. NP-184[2- (5-methyl-2-furyl) benzimidazole], a novel orally active antithrombotic agent with dual antiplatelet and anticoagulant activities. Naunyn Schmiedebergs Arch Pharmacol. 2010 Jun;381 (6) :495-505.