N-Hydroxymethyl succinimide
N-Hydroxymethyl succinimide (N-Methylolsuccinimide) is a promoiety used as a prodrug carrier for non-steroidal anti-inflammatory drugs (NSAIDs) . N-Hydroxymethyl succinimide enhances the lipophilicity of NSAIDs and reducing the gastrointestinal toxicity of NSAIDs. N-Hydroxymethyl succinimide is promising for research of anti-inflammatory drug delivery system[1].
Product Specifications
CAS Number
[5146-68-9]
Product Name Alternative
N-Methylolsuccinimide
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Purity
97.0
Smiles
C1CC(=O)N(CO)C1=O
Molecular Formula
C5H7NO3
Molecular Weight
129.11
Precautions
H315, H319
References & Citations
[1]N-hydroxymethylsuccinimide- / isatin esters of some NSAIDs as prodrugs with an improved therapeutic index. Eur J Med Chem. 1999 Jul-Aug;34 (7-8) :551-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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