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(+)-Medioresinol

Product Specifications

UNSPSC Description

(+)-Medioresinol is a furofuran type lignan with antifungal, antibacterial and lesishmanicidal activities. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. (+)-Medioresinol can reduce the cardiovascular disease risk[1][2].

Target Antigen

Apoptosis; Bacterial; Fungal; Reactive Oxygen Species

Type

Natural Products

Related Pathways

Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/plus-medioresinol.html

Purity

98.88

Solubility

DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

COC1=C(O)C(OC)=CC([C@]2([H])[C@]3([H])[C@@](CO2)([H])[C@](C4=CC(OC)=C(C=C4)O)([H])OC3)=C1

Molecular Weight

388.41

References & Citations

[1] Ji Hong Hwang, et al. (+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans. Biochimie. 2012 Aug;94(8):1784-93.|[2]Ji Hong Hwang, et al. Synergistic antibacterial and antibiofilm effect between (+)-medioresinol and antibiotics in vitro. Appl Biochem Biotechnol. 2013 Aug;170(8):1934-41.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N3307/plus-Medioresinol-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N3307/plus-Medioresinol-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

40957-99-1

Available Sizes

Curated Selection

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