Desethoxy Quetiapine (dihydrochloride)
Desethoxy Quetiapine dihydrochloride (Compound 28) is an antagonist for dopamine D2 receptor with an IC50 of 1330 nM. Desethoxy Quetiapine dihydrochloride antagonises Apomorphine -induced climbing and swimming disruption in mouse models[1].
Product Specifications
CAS Number
329218-14-6
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OCCN(CC1)CCN1C2=NC3=CC=CC=C3SC4=CC=CC=C42.Cl.Cl
Molecular Formula
C19H23Cl2N3OS
Molecular Weight
412.38
References & Citations
[1]Warawa EJ, et al., Behavioral approach to nondyskinetic dopamine antagonists: identification of seroquel. J Med Chem. 2001 Feb 1;44 (3) :372-89.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor
Available Sizes
Frequently Asked Questions
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