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BioA-IN-1

BioA-IN-1 (Compound 15) is an inhibitor of BioA, a key enzyme in the biotin synthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. BioA-IN-1 exhibits antibacterial activity but has no cytotoxicity[1].

Product Specifications

CAS Number

77820-11-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

99.24

Smiles

O=C1OC2=C(C=C1C(C3=CC=CS3)=O)C=CC(N(CC)CC)=C2

Molecular Formula

C18H17NO3S

Molecular Weight

327.40

Precautions

H302, H315, H319, H335

References & Citations

[1]Park SW, et al. Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis. Chem Biol. 2015 Jan 22;22 (1) :76-86.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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