BioA-IN-1
BioA-IN-1 (Compound 15) is an inhibitor of BioA, a key enzyme in the biotin synthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. BioA-IN-1 exhibits antibacterial activity but has no cytotoxicity[1].
Product Specifications
CAS Number
[77820-11-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
99.24
Smiles
O=C1OC2=C(C=C1C(C3=CC=CS3)=O)C=CC(N(CC)CC)=C2
Molecular Formula
C18H17NO3S
Molecular Weight
327.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Park SW, et al. Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis. Chem Biol. 2015 Jan 22;22 (1) :76-86.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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