3-Methyluracil

3-Methyluracil (Compound 5) is a pyrimidine heterocyclic compound. 3-Methyluracil can be isolated from Cordyceps bassiana. 3-Methyluracil has anti-inflammatory activity. 3-Methyluracil inhibits Luciferase (HY-P1004) activity induced by NF-κB and AP-1 and reduces the mRNA levels of COX-2 and TNF-α. 3-Methyluracil can be used for inflammatory diseases research[1].

Product Specifications

CAS Number

[608-34-4]

UNSPSC

12352005

Hazard Statement

H351

Target

COX; TNF Receptor

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Purity

95.0

Smiles

O=C1C=CNC(=O)N1C

Molecular Formula

C5H6N2O2

Molecular Weight

126.12

Precautions

H351

References & Citations

[1]Suh W, et al. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity. Biomol Ther (Seoul) . 2017 Mar 1;25 (2) :165-170.