1,2-Dimethylbenzimidazole

1,2-Dimethylbenzimidazole is a benzimidazole derivative. 1,2-Dimethylbenzimidazole exhibits antiparasitic activity with an IC50 of 0.089 μM against G. duodenalis. 1,2-Dimethylbenzimidazole can also be used in the synthesis of other bioactive compounds, such as antitumor agents[1][2].

Product Specifications

CAS Number

[2876-08-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate; Parasite

Related Pathways

Anti-infection; Others

Field of Research

Infection

Purity

98.0

Smiles

CC1=NC2=C(N1C)C=CC=C2

Molecular Formula

C9H10N2

Molecular Weight

146.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Hernández-Covarrubias C, et al. Exploring the interplay of physicochemical properties, membrane permeability and giardicidal activity of some benzimidazole derivatives. Eur J Med Chem. 2012 Jun;52:193-204.|[2]Gümüş F, et al. Synthesis, cytotoxic activity on MCF-7 cell line and mutagenic activity of platinum (II) complexes with 2-substituted benzimidazole ligands. Eur J Med Chem. 2003 May;38 (5) :473-80.