Mg (II) -EDTA (disodium tetrahydrate)

Mg (II) -EDTA disodium tetrahydrate is a reversible non-covalent activator of fructose diphosphatase (Km=0.9 μM) . Mg (II) -EDTA disodium tetrahydrate synergistically activates fructose diphosphatase with free Mg2+, promotes the hydrolysis of fructose-1,6-bisphosphate at pH≤8, and plays a role in enhancing the activity of key enzymes in gluconeogenesis[1][2].

Product Specifications

CAS Number

[29932-54-5]

Product Name Alternative

Ethylenediaminetetraacetic acid magnesium (disodium tetrahydrate)

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Purity

99.0

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C1[O-][Mg+2]([N]2(C1)CC3=O)([O-]3)([O-]C4=O)([O-]5)[N](C4)(CC2)CC5=O.O.[Na+].O.O.O.[Na+]

Molecular Formula

C10H20MgN2Na2O12

Molecular Weight

430.56

Precautions

H302, H315, H319, H335

References & Citations

[1]J S Rosenberg, et al. Activation of rabbit kidney fructose diphosphatase by Mg-EDTA, Mn-EDTA and Co-EDTA complexes. Arch Biochem Biophys. 1973, 154. 1.|[2]Zhou Haojie, et al. Purification of diphenylamine sulfide. China, CN112830904 A 2021-05-25.