4,4'-Methylenebis (2,6-di-tert-butylphenol)
4,4'-Methylenebis (2,6-di-tert-butylphenol) (4,4-MBP) is a bisphenol compound. 4,4'-Methylenebis (2,6-di-tert-butylphenol) acts as an inhibitor of sarco/endoplasmic reticulum calcium ATPase (SERCA) with an IC50 value of 17 μM. 4,4'-Methylenebis (2,6-di-tert-butylphenol) can be used in the research of diseases related to calcium homeostasis[1].
Product Specifications
CAS Number
[118-82-1]
Product Name Alternative
4,4-MBP
UNSPSC
12352005
Hazard Statement
H315, H319, H413
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Metabolic Disease
Purity
99.83
Smiles
CC(C)(C)C1=C(C(=CC(=C1)CC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C)C(C)(C)C)O
Molecular Formula
C29H44O2
Molecular Weight
424.66
Precautions
H315, H319, H413
References & Citations
[1]Woeste M, et al. Structural requirements for inhibitory effects of bisphenols on the activity of the sarco/endoplasmic reticulum calcium ATPase. Bioorg Med Chem. 2013 Jul 1;21 (13) :3927-33.
Shipping Conditions
Room Temperature
Storage Conditions
RT, stored under nitrogen
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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