Acetyl tetrapeptide-3

Acetyl tetrapeptide-3 is a synthetic peptide. Acetyl tetrapeptide-3 enhances the adhesion of hair follicles to the scalp but also promotes the development of new hair follicles. Acetyl tetrapeptide-3 stimulates the synthesis of collagen III in hair follicles. Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and ginseng extracts, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring[1][2][3].

Product Specifications

CAS Number

[827306-88-7]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Others

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

98.60

Solubility

H2O : 116.67 mg/mL (ultrasonic)

Smiles

NCCCC[C@@H](C(N)=O)NC([C@@H](NC(CNC([C@@H](NC(C)=O)CCCCN)=O)=O)CC1=CN=CN1)=O

Molecular Formula

C22H39N9O5

Molecular Weight

509.60

Precautions

H302, H315, H319, H335

References & Citations

[1]Suparuj Lueangarun, et al. An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial. J Clin Aesthet Dermatol. 2020 Oct;13 (10) :32-37.|[2]Bui Thi Phuong Hai, et al., (2025) . TOTAL SYNTHESIS OF THE ACTIVE INGREDIENT ACETYL TETRAPEPTIDE-3 FOR HAIR LOSS TREATMENT AND SCALP CARE. Natural sciences 70 (1) .|[3]Li-Wei Tian, et al., Co-delivery of bioactive peptides by nanoliposomes for promotion of hair growth, Journal of Drug Delivery Science and Technology, Volume 72, 2022, 103381, ISSN 1773-2247.