Sulfabenz

Sulfabenz (Compound 9) is an amine-substituted N1-phenylsulfonyl indole derivative. Sulfabenz has binding activity to human 5-HT6 serotonin receptor (Ki: 200 nM) . Sulfabenz can be used to study the ligand binding mechanism of 5-HT6 receptor and 5-HT6 receptor-related neurological diseases[1].

Product Specifications

CAS Number

127-77-5

UNSPSC

12352005

Hazard Statement

H227, H301

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

95.00

Smiles

C1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N

Molecular Formula

C12H12N2O2S

Molecular Weight

248.31

Precautions

H227, H301

References & Citations

[1]Pullagurla M, et al. Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors. Bioorg Med Chem Lett. 2005 Dec 1;15 (23) :5298-302.